Pranks and tricks include setting traps, leaving slippery items on the floor, smearing paintings, and much more. Cameras from a TV show that Woody is on tracks his every move and prank.

The object of the game is to sneak around the neighbor's house and perform tricks and pranks on him. The purpose of the game is for Woody to take revenge on his new neighbor by making his life absolutely miserable. One day, a new neighbor takes up residence next door, and it turns out the neighbor is quite the nuisance. In Neighbours from Hell, the player plays as the main character, 'Woody,' who enjoys life living in an average neighborhood. Neighbours from Hell is a secret pleasure for anyone who has ever had to unfortunately reside next to an unruly neighbor.